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KMID : 1207720160080010001
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Clinics in Orthopedic Surgery
2016 Volume.8 No. 1 p.1 ~ p.8
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Stem Cell Therapy for the Treatment of Hip Osteonecrosis: A 30-Year Review of Progress
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Philippe Hernigou
Matthieu Trousselier
Francois Roubineau
Charlie Bouthors
Nathalie Chevallier
Helene Rouard
Charles-Henri Flouzat-Lachaniette
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Abstract
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Avascular necrosis of the femoral head is caused by a multitude of etiologic factors and is associated with collapse with a risk of hip arthroplasty in younger populations. A focus on early disease management with the use of stem cells was proposed as early as 1985 by the senior author (PH). We undertook a systematic review of the medical literature to examine the progress in cell therapy during the last 30 years for the treatment of early stage osteonecrosis
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KEYWORD
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Hip, Osteonecrosis, Cell therapy, Mesenchymal stromal cells, Tissue engineering
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